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Pilot Trial of Immunoglobulin Versus Plasma Exchange in Patients with Guillain-Barre Syndrome Neurol 46:100-103, Bril,V.,et al, 1996 See this aricle in Pubmed Article Abstract We compared intravenous immunoglobulin(IVIG)and plasma exchange(PLEX)in the treatment of 50 patients with Guillain-Barre syndrome(GBS).Standard outcome measures did not differ for the two groups.Sixty-one percent of the PLEX-treated group and 69%of the IVIG treated group improved by one disability grade at 1 month.The complication rate was higher in the PLEX- treated group.We conclude that the efficacy of IVIG in the treatment of GBS is comparable with that of PLEX and that it can be used safely, although we had a small number of patients.We did not observe a higher relapse rate with IVIG.The usefulness of combination therapy is unknown at this time.

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(click to filter results - removes previous filter) adverse drug reaction gammaglobulin therapy,intravenous Guillain Barre syndrome plasmapheresis plasmapheresis,complications of treatment of neurologic disorder

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